Fluorescently labeled nuclear morphology is highly informative of neurotoxicity

Neurotoxicity can be detected in live microscopy by morphological changes such as retraction of neurites, fragmentation, blebbing of the neuronal soma and ultimately the disappearance of fluorescently labeled neurons. However, quantification of these features is often difficult, low-throughput, and...

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Detalhes bibliográficos

Principais autores:	Shijie Wang, Jeremy W. Linsley, Drew A. Linsley, Josh Lamstein, Steven Finkbeiner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-08-01
Colecção:	Frontiers in Toxicology
Assuntos:	cell death microscopy light convolutional neural network genetically encoded biosensor live microscopy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/ftox.2022.935438/full
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