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Fluorescently labeled nuclear morphology is highly informative of neurotoxicity

Neurotoxicity can be detected in live microscopy by morphological changes such as retraction of neurites, fragmentation, blebbing of the neuronal soma and ultimately the disappearance of fluorescently labeled neurons. However, quantification of these features is often difficult, low-throughput, and...

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Автори: Shijie Wang, Jeremy W. Linsley, Drew A. Linsley, Josh Lamstein, Steven Finkbeiner
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2022-08-01
Серія:Frontiers in Toxicology
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Онлайн доступ:https://www.frontiersin.org/articles/10.3389/ftox.2022.935438/full
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