Mechanism and regulation of DNA damage recognition in nucleotide excision repair

Abstract Nucleotide excision repair (NER) is a versatile DNA repair pathway, which can remove an extremely broad range of base lesions from the genome. In mammalian global genomic NER, the XPC protein complex initiates the repair reaction by recognizing sites of DNA damage, and this depends on detec...

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Bibliografiske detaljer

Principais autores:	Masayuki Kusakabe, Yuki Onishi, Haruto Tada, Fumika Kurihara, Kanako Kusao, Mari Furukawa, Shigenori Iwai, Masayuki Yokoi, Wataru Sakai, Kaoru Sugasawa
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2019-01-01
Serier:	Genes and Environment
Fag:	Nucleotide excision repair DNA damage recognition XPC TFIIH XPA UV-DDB
Online adgang:	http://link.springer.com/article/10.1186/s41021-019-0119-6
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