Adiponectin ameliorates hypertrophic scar by inhibiting Yes-associated protein transcription through SIRT1-mediated deacetylation of C/EBPβ and histone H3

Summary: The clinical correlation between adiponectin (APN) signal and hypertrophic scar (HS) remains unclear. Here, we found significantly reduced expression of APN receptors (AdipoR1/2) in HS tissues and derived fibroblasts (HFs), suggesting that HS formation may be associated with APN/AdipoR1/2 d...

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Dettagli Bibliografici

Autori principali:	Jian Zhang, Yan Li, Jiaqi Liu, Fu Han, Jihong Shi, Gaofeng Wu, Kejia Wang, Kuo Shen, Ming Zhao, Xiaowen Gao, Chenyang Tian, Yunchuan Wang, Ke Tao, Dahai Hu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-10-01
Serie:	iScience
Soggetti:	Biological sciences molecular biology molecular mechanism of gene regulation
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589004222015085
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