An NAD+-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39
Summary: Ubiquitin specific protease 39 (USP39), an ortholog of Sad1p in yeast, is essential for spliceosome assembly during pre-mRNA splicing in human. Although it is known that USP39 is upregulated and plays an oncogenic role in hepatocellular carcinoma (HCC), the underlying mechanism remains unkn...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2020-08-01
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| シリーズ: | iScience |
| 主題: | |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S2589004220305381 |
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