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Nicotinamide Supplementation during the In Vitro Maturation of Oocytes Improves the Developmental Competence of Preimplantation Embryos: Potential Link to SIRT1/AKT Signaling

Nicotinamide (NAM), the amide form of vitamin B3, plays pivotal roles in regulating various cellular processes including energy production and maintenance of genomic stability. The current study aimed at deciphering the effect of NAM, when administered during in vitro maturation (IVM), on the develo...

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Autori principali: Marwa El Sheikh, Ahmed Atef Mesalam, Muhammad Idrees, Tabinda Sidrat, Ayman Mesalam, Kyeong-Lim Lee, Il-Keun Kong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-06-01
Serie:Cells
Soggetti:
Nicotinamide
AKT
SIRT1
hatching
maturation
ICM
Accesso online:https://www.mdpi.com/2073-4409/9/6/1550
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