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The downregulation of RIZ1 activates the AKT/mTOR in pregnant women with obesity

Abstract Riz1 knockout mice demonstrated obesity with activation of the V-Akt murine thymoma viral oncogene homolog (PKB) (AKT)/mechanistic target of rapamycin (mTOR) pathway. Whether the decrease in RIZ1 and the activation of AKT/mTOR exist in pregnant women with obesity is still unknown. This stud...

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Auteurs principaux: Xiaolei Xie, Jiahui Yan, Jinghong Zhang, Xiaoling Huang, Jiaxing Li
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-12-01
Collection:Scientific Reports
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Accès en ligne:https://doi.org/10.1038/s41598-025-28714-y
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