HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury

Summary: Activated inflammation and pyroptosis in macrophage are closely associated with acute lung injury (ALI). Histone deacetylase 3 (HDAC3) serves as an important enzyme that could repress gene expression by mediating chromatin remodeling. In this study, we found that HDAC3 was highly expressed...

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Bibliografische Detailangaben

Hauptverfasser:	Ning Li, Bohao Liu, Ruyuan He, Guorui Li, Rui Xiong, Tinglv Fu, Donghang Li, Chenzhen Xu, Bo Wang, Qing Geng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-07-01
Schriftenreihe:	iScience
Schlagworte:	Biochemistry Molecular biology
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S258900422301235X
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