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Targeted intervention of tumor microenvironment with HDAC inhibitors and their combination therapy strategies

Abstract Histone deacetylation represents a significant epigenetic mechanism that involves the removal of acetyl groups from histones, subsequently influencing gene transcription. Overexpression of histone deacetylases (HDACs) is prevalent across various cancer types, positioning HDAC inhibitors as...

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Bibliografiset tiedot
Päätekijät: Wanli Zhang, Luqi Ge, Yiwen Zhang, Zhentao Zhang, Wen Zhang, Feifeng Song, Ping Huang, Tong Xu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2025-02-01
Sarja:European Journal of Medical Research
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Linkit:https://doi.org/10.1186/s40001-025-02326-8
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