Targeted intervention of tumor microenvironment with HDAC inhibitors and their combination therapy strategies

Abstract Histone deacetylation represents a significant epigenetic mechanism that involves the removal of acetyl groups from histones, subsequently influencing gene transcription. Overexpression of histone deacetylases (HDACs) is prevalent across various cancer types, positioning HDAC inhibitors as...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Wanli Zhang, Luqi Ge, Yiwen Zhang, Zhentao Zhang, Wen Zhang, Feifeng Song, Ping Huang, Tong Xu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	European Journal of Medical Research
Schlagworte:	Histone deacetylase Histone deacetylase inhibitors Tumor Tumor microenvironment
Online-Zugang:	https://doi.org/10.1186/s40001-025-02326-8
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!