New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease Treatment

New hybrids of 4-amino-2,3-polymethylenequinoline with different sizes of the aliphatic ring linked to butylated hydroxytoluene (BHT) by enaminoalkyl (<b>7</b>) or aminoalkyl (<b>8</b>) spacers were synthesized as potential multifunctional agents for Alzheimer’s disease (AD) treatment. All compounds...

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Egile Nagusiak:	Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Irina I. Faingold, Darya A. Poletaeva, Yuliya V. Soldatova, Raisa A. Kotelnikova, Igor V. Serkov, Anatoly K. Ustinov, Alexey N. Proshin, Eugene V. Radchenko, Vladimir A. Palyulin, Rudy J. Richardson
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2020-12-01
Saila:	Molecules
Gaiak:	4-amino-2,3-polymethylenequinolines butylated hydroxytoluene (BHT) acetylcholinesterase (AChE) butyrylcholinesterase (BChE) antioxidants neuroprotection
Sarrera elektronikoa:	https://www.mdpi.com/1420-3049/25/24/5891
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