Machine learning uncovers the transcriptional regulatory network for the production host Streptomyces albidoflavus

Summary: Streptomyces albidoflavus is a widely used strain for natural product discovery and production through heterologous biosynthetic gene clusters (BGCs). However, the transcriptional regulatory network (TRN) and its impact on secondary metabolism remain poorly understood. Here, we characterize...

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Autors principals:	Mathias Jönsson, Renata Sigrist, Tetiana Gren, Mykhaylo Semenov Petrov, Nils Emil Junge Marcussen, Anna Svetlova, Pep Charusanti, Peter Gockel, Bernhard O. Palsson, Lei Yang, Emre Özdemir
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-03-01
Col·lecció:	Cell Reports
Matèries:	CP: Microbiology CP: Molecular biology
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124725001639
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