Machine learning uncovers the transcriptional regulatory network for the production host Streptomyces albidoflavus

Summary: Streptomyces albidoflavus is a widely used strain for natural product discovery and production through heterologous biosynthetic gene clusters (BGCs). However, the transcriptional regulatory network (TRN) and its impact on secondary metabolism remain poorly understood. Here, we characterize...

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Hlavní autoři:	Mathias Jönsson, Renata Sigrist, Tetiana Gren, Mykhaylo Semenov Petrov, Nils Emil Junge Marcussen, Anna Svetlova, Pep Charusanti, Peter Gockel, Bernhard O. Palsson, Lei Yang, Emre Özdemir
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-03-01
Edice:	Cell Reports
Témata:	CP: Microbiology CP: Molecular biology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124725001639
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