Probing Differences in Gene Essentiality Between the Human and Animal Adapted Lineages of the Mycobacterium tuberculosis Complex Using TnSeq

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, however few studies have probed differences in ge...

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Autori principali:	Amanda J. Gibson, Ian J. Passmore, Valwynne Faulkner, Dong Xia, Irene Nobeli, Jennifer Stiens, Sam Willcocks, Taane G. Clark, Ben Sobkowiak, Dirk Werling, Bernardo Villarreal-Ramos, Brendan W. Wren, Sharon L. Kendall
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-12-01
Serie:	Frontiers in Veterinary Science
Soggetti:	TnSeq mycobacteria one health essential genes CRISPRi mycobacterium bovis
Accesso online:	https://www.frontiersin.org/articles/10.3389/fvets.2021.760717/full
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