Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma

Mast cells (MC) have been identified in human lung adenocarcinoma (LADC) tissues, but their functional role has not been investigated in vivo. For this, we applied three mouse models of KRAS-mutant LADC to two different MC-deficient mouse strains (cKitWsh and Cpa3.Cre). Moreover, we derived MC gene...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ioannis Lilis, Giannoula Ntaliarda, Vassilios Papaleonidopoulos, Georgia A Giotopoulou, Maria Oplopoiou, Antonia Marazioti, Magda Spella, Sebastian Marwitz, Torsten Goldmann, Vasiliki Bravou, Ioanna Giopanou, Georgios T. Stathopoulos
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2019-07-01
Цуврал:	OncoImmunology
Нөхцлүүд:	carboxypeptidase 3/mutation/il 1β/lung cancer/urethane
Онлайн хандалт:	http://dx.doi.org/10.1080/2162402X.2019.1593802
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!