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Beneficial impact of CCL2 and CCL12 neutralization on experimental malignant pleural effusion.

Using genetic interventions, we previously determined that C-C motif chemokine ligand 2 (CCL2) promotes malignant pleural effusion (MPE) formation in mice. Here we conducted preclinical studies aimed at assessing the specific therapeutic potential of antibody-mediated CCL2 blockade against MPE. For...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Antonia Marazioti, Chrysoula A Kairi, Magda Spella, Anastasios D Giannou, Sophia Magkouta, Ioanna Giopanou, Vassilios Papaleonidopoulos, Ioannis Kalomenidis, Linda A Snyder, Dimitrios Kardamakis, Georgios T Stathopoulos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3743892?pdf=render
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