Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage

Edaravone dexborneol is a novel neuroprotective drug that comprises edaravone and (+)-borneol in a 4:1 ratio. Phase II and III studies have demonstrated that Chinese patients treated with edaravone dexborneol within 48 h of AIS onset have better functional outcomes than those treated with edaravone...

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Autors principals:	Qian Chen, Yichen Cai, Xiaoyu Zhu, Jing Wang, Feng Gao, Mingfeng Yang, Leilei Mao, Zongyong Zhang, Baoliang Sun
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-04-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	oxidative stress subarachnoid hemorrhage edaravone dexborneol 4-HNE edaravone
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2022.848529/full
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