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Edaravone dexborneol attenuates oxidative stress in experimental subarachnoid hemorrhage via Keap1/Nrf2 signaling pathway

BackgroundSubarachnoid hemorrhage (SAH) serves as a disease characterized by high incidence rate, which is exceedingly prevalent and severe. Presently, there is no unambiguous or efficacious intervention for the neurological impairment following SAH. Administering multi-targeted neuroprotective agen...

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Principais autores: Kunyuan Zhu, Shijun Bi, Zechao Zhu, Wenxu Zhang, Xinyu Yang, Jiashuo Li, Guobiao Liang, Chunyong Yu, Pengyu Pan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Pharmacology
Fag:
subarachnoid hemorrhage
early brain injury
edaravone dexborneol
oxidative stress
KEAP1
Nrf2
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1342226/full
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