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Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage

Abstract Edaravone dexborneol (EDB) is widely recognized for its anti-inflammatory and antioxidant properties and is clinically applied in the treatment of acute cerebral infarction. Ferroptosis is a critical process in the pathophysiology of brain injury following intracerebral hemorrhage (ICH). Ho...

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Principais autores: Han Li, Xiang Li, Mingzhi Li, Wenxin Li, Jinghui Wei, Yuming Huang, Haiqing Yan, Juntang Lin, Ping Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-05-01
coleção:Scientific Reports
Assuntos:
Edaravone dexborneol
Intracerebral hemorrhage
Ferroptosis
P53
GPX4
Acesso em linha:https://doi.org/10.1038/s41598-025-99187-2
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