Further Probing of Cu²⁺-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes

Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu²⁺ ions in a site-specific manner. These artificial enzymes are designed to force the formation of a bulge in the RNA target, the sequence of...

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Detalles Bibliográficos

Principais autores:	Olivia Luige, Merita Murtola, Alice Ghidini, Roger Strömberg
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2019-02-01
Series:	Molecules
Assuntos:	artificial ribonuclease peptide nucleic acid RNA cleavage catalysis
Acceso en liña:	https://www.mdpi.com/1420-3049/24/4/672
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