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Further Probing of Cu<sup>2+</sup>-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes

Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu<sup>2+</sup> ions in a site-specific manner. These artificial enzymes are designed to force the formation of a bulge in the RNA target, the sequence of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Olivia Luige, Merita Murtola, Alice Ghidini, Roger Strömberg
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-02-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/24/4/672
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