Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress
The mitochondrial unfolded protein response (mitoUPR) is a stress response pathway that responds to mitochondrial insults by altering gene expression to recover mitochondrial homeostasis. The mitoUPR is mediated by the stress-activated transcription factor ATFS-1 (activating transcription factor ass...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2025-04-01
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| Serie: | Open Biology |
| Soggetti: | |
| Accesso online: | https://royalsocietypublishing.org/doi/10.1098/rsob.240358 |
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