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Mild mitochondrial impairment activates overlapping longevity pathways converging on the flavin-containing monooxygenase FMO-2

A mild impairment of mitochondrial function activates the hypoxia inducible factor (HIF-1)-mediated hypoxia stress response pathway leading to a HIF-1-dependent increase in lifespan. Lifespan extension resulting from HIF-1 stabilization is dependent on activation of flavin-containing monooxygenase-2...

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I tiakina i:
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Kaituhi matua: Jeremy M. Van Raamsdonk
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2026-03-01
Rangatū:Frontiers in Aging
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fragi.2026.1808540/full
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