Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences

Abstract Background Proline racemase (PRAC) enzymes of Trypanosoma cruzi (TcPRAC), the agent of Chagas disease, and Trypanosoma vivax (TvPRAC), the agent of livestock trypanosomosis, have been implicated in the B-cells polyclonal activation contributing to immunosuppression and the evasion of host d...

Descripció completa

Dades bibliogràfiques

Autors principals:	Zuleima C Caballero, Andre G Costa-Martins, Robson C Ferreira, João M P Alves, Myrna G Serrano, Erney P Camargo, Gregory A Buck, Paola Minoprio, Marta M G Teixeira
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2015-04-01
Col·lecció:	Parasites & Vectors
Matèries:	Proline racemase Trypanosoma cruzi Trypanosoma vivax Trypanosoma rangeli Horizontal gene transfer Gene loss
Accés en línia:	https://doi.org/10.1186/s13071-015-0829-y
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!