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Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences

Abstract Background Proline racemase (PRAC) enzymes of Trypanosoma cruzi (TcPRAC), the agent of Chagas disease, and Trypanosoma vivax (TvPRAC), the agent of livestock trypanosomosis, have been implicated in the B-cells polyclonal activation contributing to immunosuppression and the evasion of host d...

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Príomhchruthaitheoirí: Zuleima C Caballero, Andre G Costa-Martins, Robson C Ferreira, João M P Alves, Myrna G Serrano, Erney P Camargo, Gregory A Buck, Paola Minoprio, Marta M G Teixeira
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2015-04-01
Sraith:Parasites & Vectors
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s13071-015-0829-y
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