Cardiac troponin and tropomyosin bind to F‐actin cooperatively, as revealed by fluorescence microscopy

In cardiac muscle, binding of troponin (Tn) and tropomyosin (Tpm) to filamentous (F)‐actin forms thin filaments capable of Ca2+‐dependent regulation of contraction. Tpm binds to F‐actin in a head‐to‐tail fashion, while Tn stabilizes these linkages. Valuable structural and functional information has...

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Hlavní autoři:	Christopher Solís, John M. Robinson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2020-07-01
Edice:	FEBS Open Bio
Témata:	binding isotherm Monte Carlo protein–protein interactions quantitative imaging stochastic simulation
On-line přístup:	https://doi.org/10.1002/2211-5463.12876
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