Cardiac troponin and tropomyosin bind to F‐actin cooperatively, as revealed by fluorescence microscopy
In cardiac muscle, binding of troponin (Tn) and tropomyosin (Tpm) to filamentous (F)‐actin forms thin filaments capable of Ca2+‐dependent regulation of contraction. Tpm binds to F‐actin in a head‐to‐tail fashion, while Tn stabilizes these linkages. Valuable structural and functional information has...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2020-07-01
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| Serier: | FEBS Open Bio |
| Fag: | |
| Online adgang: | https://doi.org/10.1002/2211-5463.12876 |
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