Cardiac troponin and tropomyosin bind to F‐actin cooperatively, as revealed by fluorescence microscopy

In cardiac muscle, binding of troponin (Tn) and tropomyosin (Tpm) to filamentous (F)‐actin forms thin filaments capable of Ca2+‐dependent regulation of contraction. Tpm binds to F‐actin in a head‐to‐tail fashion, while Tn stabilizes these linkages. Valuable structural and functional information has...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Christopher Solís, John M. Robinson
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Wiley 2020-07-01
श्रृंखला:	FEBS Open Bio
विषय:	binding isotherm Monte Carlo protein–protein interactions quantitative imaging stochastic simulation
ऑनलाइन पहुंच:	https://doi.org/10.1002/2211-5463.12876
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