Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality

Abstract Aims Somatic mutations in haematopoietic stem cells can lead to the clonal expansion of mutated blood cells, known as clonal haematopoiesis (CH). Mutations in the most prevalent driver genes DNMT3A and TET2 with a variant allele frequency (VAF) ≥ 2% have been associated with atherosclerosis...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Katharina C. Kiefer, Sebastian Cremer, Evangelia Pardali, Birgit Assmus, Khalil Abou‐El‐Ardat, Klara Kirschbaum, Lena Dorsheimer, Tina Rasper, Alexander Berkowitsch, Hubert Serve, Stefanie Dimmeler, Andreas M. Zeiher, Michael A. Rieger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2021-06-01
Colecção:	ESC Heart Failure
Assuntos:	Blood cell mutations Clonal haematopoiesis Heart failure Age
Acesso em linha:	https://doi.org/10.1002/ehf2.13297
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!