Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality

Abstract Aims Somatic mutations in haematopoietic stem cells can lead to the clonal expansion of mutated blood cells, known as clonal haematopoiesis (CH). Mutations in the most prevalent driver genes DNMT3A and TET2 with a variant allele frequency (VAF) ≥ 2% have been associated with atherosclerosis...

Descripció completa

Dades bibliogràfiques

Autors principals:	Katharina C. Kiefer, Sebastian Cremer, Evangelia Pardali, Birgit Assmus, Khalil Abou‐El‐Ardat, Klara Kirschbaum, Lena Dorsheimer, Tina Rasper, Alexander Berkowitsch, Hubert Serve, Stefanie Dimmeler, Andreas M. Zeiher, Michael A. Rieger
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2021-06-01
Col·lecció:	ESC Heart Failure
Matèries:	Blood cell mutations Clonal haematopoiesis Heart failure Age
Accés en línia:	https://doi.org/10.1002/ehf2.13297
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!