Improved inference of site-specific positive selection under a generalized parametric codon model when there are multinucleotide mutations and multiple nonsynonymous rates

Abstract Background An excess of nonsynonymous substitutions, over neutrality, is considered evidence of positive Darwinian selection. Inference for proteins often relies on estimation of the nonsynonymous to synonymous ratio (ω = d N/d S) within a codon model. However, to ease computational difficu...

詳細記述

書誌詳細

主要な著者:	Katherine A. Dunn, Toby Kenney, Hong Gu, Joseph P. Bielawski
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2019-01-01
シリーズ:	BMC Evolutionary Biology
主題:	Codon model Positive selection Protein evolution Multiple nucleotide mutations Multiple nonsynonymous rates M-series models
オンライン･アクセス:	http://link.springer.com/article/10.1186/s12862-018-1326-7
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!