MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.
Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degradation...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Public Library of Science (PLoS)
2014-02-01
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| Rangatū: | PLoS Genetics |
| Urunga tuihono: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004188&type=printable |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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