MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degradation...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science (PLoS) 2014-02-01
سلاسل:	PLoS Genetics
الوصول للمادة أونلاين:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004188&type=printable
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!