MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degradation...

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Egile Nagusiak:	Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Public Library of Science (PLoS) 2014-02-01
Saila:	PLoS Genetics
Sarrera elektronikoa:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004188&type=printable
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