In silico design of novel pyridazine derivatives as balanced multifunctional agents against Alzheimer’s disease
Abstract Alzheimer’s disease (AD) necessitates innovative therapeutic approaches that target its multifaceted pathology. This study investigates a series of 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as potential multi-target ligands for AD, aiming to simultaneously inhibit acet...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2025-05-01
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| Collection: | Scientific Reports |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1038/s41598-025-98182-x |
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