Structural basis to identify a target site in Shiga toxin for the inhibitor discovery against growth of Shiga toxin-producing E. coli

Abstract Background Certain peptides that bind Shiga toxin 2 (Stx2) have been reported to treat Shiga toxin-producing Escherichia coli (STEC) infections. However, their mechanisms of action remain unknown. STEC infections lead to serious diseases, such as hemolytic uremic syndrome, in humans. Antibi...

Descripció completa

Dades bibliogràfiques

Autors principals:	Anuja Prabhudesai, Samir Shaikh, Kayasth Zarna Ashwinbhai, Reeshu Gupta
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2024-03-01
Col·lecció:	Bulletin of the National Research Centre
Matèries:	Shiga toxin-producing E. coli Tetravalent peptide Antibiotics Ribosome binding site Ribosomal P-stalk
Accés en línia:	https://doi.org/10.1186/s42269-024-01190-6
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!