Phase I dose-escalation oncology trials with sequential multiple schedules

Abstract Background Conventional methods for phase I dose-escalation trials in oncology are based on a single treatment schedule only. More recently, however, multiple schedules are more frequently investigated in the same trial. Methods Here, we consider sequential phase I trials, where the trial p...

Descripció completa

Dades bibliogràfiques

Autors principals:	Burak Kürsad Günhan, Sebastian Weber, Abdelkader Seroutou, Tim Friede
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-04-01
Col·lecció:	BMC Medical Research Methodology
Matèries:	Phase I dose-escalation trials Multiple treatment schedules PK models Bayesian statistics
Accés en línia:	https://doi.org/10.1186/s12874-021-01218-9
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!