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Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4

The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivation domain (TAD) of MYC protein to engineer the hum...

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I tiakina i:
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Ngā kaituhi matua: Ling Wang, Delun Huang, Chang Huang, Yexuan Yin, Kaneha Vali, Ming Zhang, Young Tang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2017-12-01
Rangatū:Stem Cell Research
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S1873506117302180
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