Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4
The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivation domain (TAD) of MYC protein to engineer the hum...
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| Principais autores: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2017-12-01
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| 叢編: | Stem Cell Research |
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S1873506117302180 |
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