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Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4

The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivation domain (TAD) of MYC protein to engineer the hum...

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書誌詳細
主要な著者: Ling Wang, Delun Huang, Chang Huang, Yexuan Yin, Kaneha Vali, Ming Zhang, Young Tang
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017-12-01
シリーズ:Stem Cell Research
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1873506117302180
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