The Diarylheptanoid Curcumin Induces MYC Inhibition and Cross-Links This Oncoprotein to the Coactivator TRRAP
The c-Myc protein (MYC) is a transcription factor with strong oncogenic potential controlling fundamental cellular processes. In most human tumors, MYC is overexpressed by enhanced transcriptional activation, gene amplification, chromosomal rearrangements, or increased protein stabilization. To phar...
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| Huvudupphov: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Frontiers Media S.A.
2021-04-01
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| Serie: | Frontiers in Oncology |
| Ämnen: | |
| Länkar: | https://www.frontiersin.org/articles/10.3389/fonc.2021.660481/full |
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