The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

The c-Myc protein functions as a transcription factor to facilitate oncogenic transformation; however, the biochemical and genetic pathways leading to transformation remain undefined. We demonstrate here that the recently described c-Myc cofactor TRRAP recruits histone acetylase activity, which is c...

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Main Authors: McMahon, Steven B., Wood, Marcelo A., Cole, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC85131/
https://ncbi.nlm.nih.gov/pubmed/10611234
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