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The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

The c-Myc protein functions as a transcription factor to facilitate oncogenic transformation; however, the biochemical and genetic pathways leading to transformation remain undefined. We demonstrate here that the recently described c-Myc cofactor TRRAP recruits histone acetylase activity, which is c...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: McMahon, Steven B., Wood, Marcelo A., Cole, Michael D.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.556-562.2000
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