AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation
Adeno-associated virus (AAV) vectors are considered efficient vectors for gene transfer, as illustrated by recent successful clinical trials targeting retinal or neurodegenerative disorders. However, limitations as host immune responses to AAV capsid or transduction of limited regions must still be...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2021-03-01
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| Seri Bilgileri: | Molecular Therapy: Methods & Clinical Development |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2329050121000188 |
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