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Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer

Preventing untoward immune responses against a specific antigen is a major challenge in different clinical settings such as gene therapy, transplantation, or autoimmunity. Following intramuscular delivery of recombinant adeno-associated virus (rAAV)-derived vectors, transgene rejection can be a road...

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Bibliografiske detaljer
Principais autores: Aurélie Moreau, Céline Vandamme, Mercedes Segovia, Marie Devaux, Mickaël Guilbaud, Gaëlle Tilly, Nicolas Jaulin, Johanne Le Duff, Yan Cherel, Jack-Yves Deschamps, Ignacio Anegon, Philippe Moullier, Maria Cristina Cuturi, Oumeya Adjali
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014-01-01
Serier:Molecular Therapy: Methods & Clinical Development
Online adgang:http://www.sciencedirect.com/science/article/pii/S2329050116300948
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