T160‐phosphorylated CDK2 defines threshold for HGF‐dependent proliferation in primary hepatocytes

Abstract Liver regeneration is a tightly controlled process mainly achieved by proliferation of usually quiescent hepatocytes. The specific molecular mechanisms ensuring cell division only in response to proliferative signals such as hepatocyte growth factor (HGF) are not fully understood. Here, we...

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מידע ביבליוגרפי

Principais autores:	Stephanie Mueller, Jérémy Huard, Katharina Waldow, Xiaoyun Huang, Lorenza A D'Alessandro, Sebastian Bohl, Kathleen Börner, Dirk Grimm, Steffen Klamt, Ursula Klingmüller, Marcel Schilling
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Springer Nature 2015-03-01
סדרה:	Molecular Systems Biology
נושאים:	G1/S transition hepatocyte proliferation HGF mathematical model threshold
גישה מקוונת:	https://doi.org/10.15252/msb.20156032
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