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Notch-Signaling Deregulation Induces Myeloid-Derived Suppressor Cells in T-Cell Acute Lymphoblastic Leukemia

Notch receptors deeply influence T-cell development and differentiation, and their dysregulation represents a frequent causative event in “T-cell acute lymphoblastic leukemia” (T-ALL). “Myeloid-derived suppressor cells” (MDSCs) inhibit host immune responses in the tumor environment, favoring cancer...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Paola Grazioli, Andrea Orlando, Nike Giordano, Claudia Noce, Giovanna Peruzzi, Behnaz Abdollahzadeh, Isabella Screpanti, Antonio Francesco Campese
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-04-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fimmu.2022.809261/full
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