Adaptive value of foot-and-mouth disease virus capsid substitutions with opposite effects on particle acid stability
Abstract Foot-and-mouth disease virus (FMDV) is a picornavirus that exhibits an extremely acid sensitive capsid. This acid lability is directly related to its mechanism of uncoating triggered by acidification inside cellular endosomes. Using a collection of FMDV mutants we have systematically analyz...
שמור ב:
| Principais autores: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Portfolio
2021-12-01
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| סדרה: | Scientific Reports |
| גישה מקוונת: | https://doi.org/10.1038/s41598-021-02757-3 |
| תגים: |
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