क्यूआर कोड

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Anaplastic lymphoma kinase (ALK; also known as ALK tyrosine kinase receptor) inhibitors (ALKi) are effective in treating lung cancer patients with chromosomal rearrangement of ALK. However, continuous treatment with ALKis invariably leads to acquired resistance in cancer cells. In this study, we pro...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Wiley 2025-04-01
श्रृंखला:Molecular Oncology
विषय:
acquired resistance
ALK inhibitors
connectivity map
emetine
transcriptome‐based drug repositioning
ऑनलाइन पहुंच:https://doi.org/10.1002/1878-0261.13738
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