Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions

BACKGROUND Patients with sickle cell disease (SCD) frequently receive RBC units stored near the end of their permissible storage duration. We aimed to determine whether RBC storage duration influences recipient hematological, metabolic, and clinical chemistry parameters.METHODS In a randomized, pros...

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Autors principals:	Matthew S. Karafin, Abby L. Grier, Ross M. Fasano, Anton Ilich, David Wichlan, Ada Chang, Sonjile M. James, Hailly E. Butler, Oleg Kolupaev, Melissa C. Caughey, Daniel J. Stephenson, Julie A. Reisz, Nigel S. Key, Joshua J. Field, Jane A. Little, Steven L. Spitalnik, Angelo D’Alessandro
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2025-09-01
Col·lecció:	The Journal of Clinical Investigation
Matèries:	Clinical Research Hematology
Accés en línia:	https://doi.org/10.1172/JCI192920
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